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PROJECT NAME: MOLNUPIRAVIR
Sr. No. Abbreviation Name Structure Quantity Cost
1. Impurity A

 

CAS No:
3258-02-4

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one

 

C9H15N3O7
Mol. Wt.: 277.23

   
2.

 

CAS No:
138421-23-5

 2-Propanone, O-(2-methyl-1-oxopropyl) Oxime

 

C7H13NO2
Mol. Wt.: 143.18

   
3.

 

CAS No:
65-46-3

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

 

C9H13N3O5
Mol. Wt.: 243.22

   
4. Impurity B

 

CAS No:
2346620-55-9

((3aR,4R,6R,6aR)-6-(4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl Isobutyrate

 

C16H23N3O7
Mol. Wt.: 369.37

   
5.

 

CAS No:
1686124-74-2

((3aR,4R,6R,6aR)-6-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl Isobutyrate

 

C16H23N3O6
Mol. Wt.: 353.37

   
6.

 

CAS No:
1955522-00-5

 4-amino-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidin-2(1H)-one sulfate

 

C12H19N3O9S
Mol. Wt.: 381.36

   
7.

 

CAS No:
NA

 Diacylated Impurity

 

C17H25N3O8
Mol. Wt.: 399.40

   
8.

 

CAS No:
58-96-8

1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4(1H,3H)-dione

 

C9H12N2O6
Mol. Wt.: 244.20

    
9.

 

CAS No:
NA

Uridine Acylation

 

C13H18N2O7
Mol. Wt.: 314.29

   
PROJECT NAME: LINAGLIPTIN
Sr. No. Abbreviation Name Structure Quantity Cost
1. Impurity A

 

CAS No:
NA:

3-methyl-Bis-3,7(2-butyn-1-yl)-8-[3-amino-piperidin-1-yl]-xanthine

 

C19H24N6O2
Mol. Wt.: 368.43

   
2. Impurity B

 

CAS No:
93703-24-3

 8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione

 

C6H5BrN4O2
Mol. Wt.: 245.03

   
3. Impurity C

 

CAS No:
NA

8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

 

C15H20N6O2
Mol. Wt.: 316.36

   
4. Impurity D

 

CAS No:
666816-98-4

 8-bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine- 2,6-dione

 

C10H9BrN4O2
Mol. Wt.: 297.11

   
5. Impurity E (Stage-II)

 

CAS No:
853029-57-9

 8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-(naphthalen-2-ylmethyl)-3,7-dihydro-1H-purine-2,6-dione

 

C20H17BrN6O2
Mol. Wt.: 453.29

   
6. Impurity F

 

CAS No:
NA

 (3R)-1-[(4-methylquinazolin-2-yl)
methyl]iperidine-3-amine

 

C15H20N4
Mol. Wt.: 256.35

    
7. Impurity G 1-[(4-methyl-quinazolin-2yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[-3-hydroxypiperidin-1-yl]-xanthine

 

C25H27N7O3
Mol. Wt.: 473.53

   
8. Impurity H (Stage-III)

 

CAS No:
668273-75-4

 1-[(4-methyl-quinazolin-2yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[(R)-3-(tert.-butyoxy carbonylamino)-piperidin-1-yl]-xanthine

 

C30H36N8O4
Mol. Wt.: 572.66

   
9. Impurity I

 

CAS No:
668270-11-9

 1-[(4-methyl-quinazolin-2yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[(S)-3-amino-piperidin-1-yl]-xanthine

 

C25H28N8O2
Mol. Wt.: 472.54

   
10. ImpurityJ

 

CAS No:
109113-72-6

 2-(Chloromethyl)-4-methylquinazoline

 

C10H9ClN2
Mol. Wt.: 192.64